Piechota-Polanczyk A, Demyanets S, Mittlboeck M, Hofmann M, Domenig CM, Neumayer C, Wojta J, Klinger M, Nanobachvili J, Huk I. The Influence of Simvastatin on NGAL, Matrix Metalloproteinases and Their Tissue Inhibitors in Human Intraluminal Thrombus and Abdominal Aortic Aneurysm Tissue Eur J Vasc Endovasc Surg. 2015 Mar 20. pii: S1078-5884(15)00103-3. doi: 10.1016/j.ejvs. 2015.02.011. PubMed PMID: 25800096 !
Stojkovic S, Kaun C, Heinz M, Krychtiuk KA, Rauscher S, Lemberger CE, de Martin R, Gröger M, Petzelbauer P, Huk I, Huber K, Wojta J, Demyanets S. Interleukin-33 induces urokinase in human endothelial cells--possible impact on angiogenesis J Thromb Haemost. 2014 Jun;12(6):948-57. doi: 10.1111/jth.12581. PubMed PMID: 24702774 !
Piechota-Polanczyk A, Demyanets S, Nykonenko O, Huk I, Mittlboeck M, Domenig CM, Neumayer C, Wojta J, Nanobachvili J, Klinger M. Decreased tissue levels of cyclophilin A, a cyclosporine a target and phospho-ERK1/2 in simvastatin patients with abdominal aortic aneurysm Eur J Vasc Endovasc Surg. 2013 Jun;45(6):682-8; doi: 10.1016/j.ejvs.2013.02.015 PubMed PMID: 23558220 !
Piechota-Polanczyk A, Goraca A, Demyanets S, Mittlboeck M, Domenig C, Neumayer C, Wojta J, Nanobachvili J, Huk I, Klinger M. Simvastatin decreases free radicals formation in the human abdominal aortic aneurysm wall via NF-κB Eur J Vasc Endovasc Surg. 2012 Aug;44(2):133-7. doi: 10.1016/j.ejvs.2012.04.020 PMID: 22694979 !
Demyanets S, Konya V, Kastl SP, Kaun C, Rauscher S, Niessner A, Pentz R, Pfaffenberger S, Rychli K, Lemberger CE, de Martin R, Heinemann A, Huk I, Gröger M, Maurer G, Huber K, Wojta J. Interleukin-33 induces expression of adhesionmolecules and inflammatory activation in human endothelial cells and in human atherosclerotic plaques Arterioscler Thromb Vasc Biol. 2011 Sep;31(9):2080-9. doi: 10.1161/ATVBAHA. 111.231431. PubMed PMID: 21737781. !
Demyanets S, Kaun C, Rychli K, Pfaffenberger S, Kastl SP, Hohensinner PJ, Rega G, Katsaros KM, Afonyushkin T, Bochkov VN, Paireder M, Huk I, Maurer G, Huber K, Wojta J. Oncostatin M-enhanced vascular endothelial growth factor expression in human vascular smooth muscle cells involves PI3K-, p38 MAPK-, Erk1/2- and STAT1/STAT3-dependent pathways and is attenuated by interferon-γ Basic Res Cardiol. 2011 Mar;106(2):217-31. doi: 10.1007/s00395-010-0141-0. PubMed PMID: 21174212 !
Wibmer A, Schoder M, Wolff KS, Prusa AM, Sahal M, Lammer J, Huk I, Polterauer P, Kretschmer G, Teufelsbauer H. Improved survival after abdominal aortic aneurysm rupture by offering both open and endovascular repair Arch Surg. 2008 Jun;143(6):544-9; discussion 550. doi: 10.1001/archsurg.143.6.544. PubMed PMID: 18559746.
Weiss TW, Kvakan H, Kaun C, Prager M, Speidl WS, Zorn G, Pfaffenberger S, Huk I, Maurer G, Huber K, Wojta J. No evidence for a direct role of Helicobacter pylori and Mycoplasma pneumoniae in carotid artery atherosclerosis. J Clin Pathol. 2006 Nov;59(11):1186-90. Epub 2006 Apr 27. PubMed PMID: 16644879; PubMed Central PMCID: PMC1860507 !
Teufelsbauer H, Polterauer P, Lammer J, Huk I, Nanobachvili J, Kretschmer G. Repair of abdominal aortic aneurysms: the benefits of offering both endovascular and open surgical techniques Perspect Vasc Surg Endovasc Ther. 2006 Sep;18(3):238-46. Review. PubMed PMID: 17172539 !
Neumayer C, Fügl A, Nanobashvili J, Blumer R, Punz A, Gruber H, Polterauer P, Huk I. Combined enzymatic and antioxidative treatment reduces ischemia-reperfusion injury in rabbit skeletal muscle. J Surg Res. 2006 Jun 15;133(2):150-8. Epub 2006 Feb 3. PubMed PMID: 16458926. ! Prusa AM, Wolff KS, Sahal M, Polterauer P, Lammer J, Kretschmer G, Huk I, Teufelsbauer H. Abdominal aortic aneurysms and concomitant diseases requiring surgical intervention: simultaneous operation vs staged treatment using endoluminal stent grafting Arch Surg. 2005 Jul;140(7):686-91. PubMed PMID: 16027335. !
Wolff KS, Prusa AM, Polterauer P, Wibmer A, Schoder M, Lammer J, Kretschmer G, Huk I, Teufelsbauer H. Endografting increases total volume of AAA repairs but not at the expense of open surgery: experience in more than 1000 patients. J Endovasc Ther. 2005 Jun;12(3):274-9. PubMed PMID: 15943501. !
Dudek D, Legutko J, Heba G, Bartus S, Partyka L, Huk I, Dembinska-Kiec A, Kaluza GL, Dubiel JS. L-arginine supplementation does not inhibit neointimalformation after coronary stenting in human beings: an intravascular ultrasound study Am Heart J. 2004 Apr;147(4):E12. PubMed PMID: 15077095. !
Nanobashvili J, Neumayer C, Fuegl A, Punz A, Blumer R, Mittlböck M, Prager M, Polterauer P, Dobrucki LW, Huk I, Malinski T. Combined L-arginine and antioxidative vitamin treatment mollifies ischemia-reperfusion injury of skeletal muscle. J Vasc Surg. 2004 Apr;39(4):868-77. PubMed PMID: 15071457 !
Nanobashvili J, Prager M, Jozkowicz A, Neumayer C, Fügl A, Blumer R, Cabaj A, Wrba F, Polterauer P, Huk I. Positive effect of treatment with synthetic steroid hormone tibolon on intimal hyperplasia and restenosis after experimentalendothelial injury of rabbit carotid artery. Eur Surg Res. 2004 Mar-Apr;36(2):74-82. PubMed PMID: 15007259 !
Józkowicz A, Dulak J, Nigisch A, Funovics P, Weigel G, Polterauer P, Huk I, Malinski T. Involvement of nitric oxide in angiogenic activities of vascular endothelial growth factor isoforms Growth Factors. 2004 Mar;22(1):19-28. PubMed PMID: 15176455. !
Józkowicz A, Nigisch A, Wegrzyn J, Weigel G, Huk I, Dulak J. Opposite effects of prostaglandin-J2 on VEGF in normoxia and hypoxia: role of HIF-1 Biochem Biophys Res Commun. 2004 Jan 30;314(1):31-8. PubMed PMID: 14715242. !
Teufelsbauer H, Prusa AM, Wolff K, Sahal M, Polterauer P, Lammer J, Hölzenbein T, Kretschmer G, Huk I. The impact of endovascular stent grafting on reducing mortality rates after surgical treatment of abdominal aortic aneurysms. Eur J Vasc Endovasc Surg. 2003 Nov;26(5):494-500. PubMed PMID: 14532876 !
Teufelsbauer H, Prusa AM, Wolff K, Sahal M, Hölzenbein T, Kretschmer G, Huk I, Polterauer P. Ruptured abdominal aortic aneurysms: status quo after a quarter century of treatment experience Wien Klin Wochenschr. 2003 Sep 15;115(15-16):584-9. German. PubMed PMID: 14531172 !
Nanobashvili J, Neumayer C, Fuegl A, Blumer R, Prager M, Sporn E, Polterauer P, Malinski T, Huk I. Development of 'no-reflow' phenomenon in ischemia/reperfusion injury: failure of active vasomotility and not simply passive vasoconstriction Eur Surg Res. 2003 Sep-Oct;35(5):417-24. PubMed PMID: 12928599
Prager MR, Hoblaj T, Nanobashvili J, Sporn E, Polterauer P, Wagner O, Böhmig HJ, Teufelsbauer H, Ploner M, Huk I. Collagen- versus gelatine-coated Dacron versus stretch PTFE bifurcation grafts for aortoiliac occlusive disease: long-term results of a prospective, randomized multicenter trial Surgery. 2003 Jul;134(1):80-5. PubMed PMID: 12874586 !
Józkowicz A, Huk I, Nigisch A, Weigel G, Dietrich W, Motterlini R, Dulak J. Heme oxygenase and angiogenic activity of endothelial cells: stimulation by carbon monoxide and inhibition by tin protoporphyrin-IX. Antioxid Redox Signal. 2003 Apr;5(2):155-62. PubMed PMID: 12716475 !
Jozkowicz A, Fügl A, Nanobashvili J, Neumayer C, Dulak J, Valentini D, Funovics P, Polterauer P, Redl H, Huk I. Delivery of high dose VEGF plasmid using fibrin carrier does not influence its angiogenic potency Int J Artif Organs. 2003 Feb;26(2):161-9. PubMed PMID: 1265335 !
Józkowicz A, Huk I, Nigisch A, Cisowski J, Weigel G, Dulak J. Prostaglandin-J(2) upregulates expression of matrix metalloproteinase-1 independently of activation of peroxisome proliferator-activated receptor-gamma Acta Biochim Pol. 2003;50(3):677-89. PubMed PMID: 14515149 !
Nanobashvili J, Neumayer C, Fügl A, Punz A, Blumer R, Prager M, Mittlböck M, Gruber H, Polterauer P, Roth E, Malinski T, Huk I. Ischemia/reperfusion injury of skeletal muscle: plasma taurine as a measure of tissue damage Surgery. 2003 Jan;133(1):91-100. PubMed PMID: 12563243 !
Teufelsbauer H, Prusa AM, Prager M, Thurnher S, Lammer J, Hölzenbein T, Kretschmer G, Huk I, Polterauer P. Endovascular treatment of a multimorbid patient with late AAA rupture after stent-graft placement: 1-year follow-up J Endovasc Ther. 2002 Dec;9(6):896-900. PubMed PMID: 12546593 !
Prager M, Türel Z, Speidl WS, Zorn G, Kaun C, Niessner A, Heinze G, Huk I, Maurer G, Huber K, Wojta J. Chlamydia pneumoniae in carotid artery atherosclerosis: a comparison of its presence in atherosclerotic plaque, healthy vessels, and circulating leukocytes from the same individuals Stroke. 2002 Dec;33(12):2756-61. PubMed PMID: 12468766 !
Teufelsbauer H, Prusa AM, Wolff K, Polterauer P, Nanobashvili J, Prager M, Hölzenbein T, Thurnher S, Lammer J, Schemper M, Kretschmer G, Huk I. Endovascular stent grafting versus open surgical operation in patients with infrarenal aortic aneurysms: a propensity score-adjusted analysis. Circulation. 2002 Aug 13;106(7):782-7. PubMed PMID: 12176947 !
Jozkowicz A, Huk I, Nigisch A, Weigel G, Weidinger F, Dulak J. Effect of prostaglandin-J(2) on VEGF synthesis depends on the induction of heme oxygenase-1 Antioxid Redox Signal. 2002 Aug;4(4):577-85. PubMed PMID: 12230869. !
Hallström S, Gasser H, Neumayer C, Fügl A, Nanobashvili J, Jakubowski A, Huk I, Schlag G, Malinski T. S-nitroso human serum albumin treatment reduces ischemia/reperfusion injury in skeletal muscle via nitric oxide release Circulation. 2002 Jun 25;105(25):3032-8. PubMed PMID: 12081999 !
Dulak J, Józkowicz A, Foresti R, Kasza A, Frick M, Huk I, Green CJ, Pachinger O, Weidinger F, Motterlini R. Heme oxygenase activity modulates vascular endothelial growth factor synthesis in vascular smooth muscle cells Antioxid Redox Signal. 2002 Apr;4(2):229-40. PubMed PMID: 12006174. !
Jozkowicz A, Dulak J, Prager M, Nanobashvili J, Nigisch A, Winter B, Weigel G, Huk I. Prostaglandin-J2 induces synthesis of interleukin-8 by endothelial cells in a PPAR-gamma independent manner. Prostaglandins Other Lipid Mediat. 2001 Oct;66(3):165-77. PubMed PMID: 11577781. !
Jozkowicz A, Cooke JP, Guevara I, Huk I, Funovics P, Pachinger O, Weidinger F, Dulak J. Genetic augmentation of nitric oxide synthase increases the vascular generation of VEGF Cardiovasc Res. 2001 Sep;51(4):773-83. PubMed PMID: 11530111 !
Prager M, Polterauer P, Böhmig HJ, Wagner O, Fügl A, Kretschmer G, Plohner M, Nanobashvili J, Huk I. Collagen versus gelatin-coated Dacron versus stretch polytetrafluoroethylene in abdominal aortic bifurcation graft surgery: results of a seven-year prospective, randomized multicenter trial Surgery. 2001 Sep;130(3):408-14. PubMed PMID: 11562661. !
Malinski T, Huk I. Measurement of nitric oxide in single cells and tissue using a porphyrinic microsensor. Curr Protoc Neurosci. 2001 May; Chapter 7:Unit7.14. doi: 10.1002/0471142301.ns0714s06. PubMed PMID: 18428525.
Huk I. Clinical research in a university hospital--how we do it in Austria Kongressbd Dtsch Ges Chir Kongr. 2001;118:801-3. German. PubMed PMID: 11824365. !
Huk I, Brovkovych V, Nanobashvili J, Neumayer C, Polterauer P, Prager M, Patton S, Malinski T. Prostaglandin E1 reduces ischemia/reperfusion injury by normalizing nitric oxide and superoxide release. Shock. 2000 Aug;14(2):234-42. PubMed PMID: 10947172 !
Polterauer P, Nanobachvili J, Fuegl A, Huk I. Vascular surgery between the millenniums. Vasa. 2000 Feb;29(1):17-27. Review. PubMed PMID: 10731884
Punz A, Nanobashvili J, Neumayer C, Blumer R, Gassner R, Fuegl A, Huk I, Roth E. Multivitamin administration before ischemia reduces ischemia-reperfusion injury in rabbit skeletal muscle Clin Nutr. 1999 Aug;18(4):219-26. PubMed PMID: 10578021. !
Huk I, Brovkovych V, Nanobashvili J, Weigel G, Neumayer C, Partyka L, Patton S, Malinski T. Bioflavonoid quercetin scavenges superoxide and increases nitric oxide concentration in ischaemia-reperfusion injury: an experimental study Br J Surg. 1998 Aug;85(8):1080-5. PubMed PMID: 9718001 !
Punz A, Nanobashvili J, Fuegl A, Huk I, Roth E. Effect of alpha-tocopherolpretreatment on high energy metabolites in rabbit skeletal muscle after ischemia-reperfusion Clin Nutr. 1998 Apr;17(2):85-7. PubMed PMID: 10205323 !
Brovkovych V, Patton S, Brovkovych S, Kiechle F, Huk I, Maliński T. In situ measurement of nitric oxide, superoxide and peroxynitrite during endotoxemia Journal Physiol Pharmacol. 1997 Dec;48(4):633-44. PubMed PMID: 9444612 IF: 0,962 ! Dembinska-Kiec A, Dulak J, Partyka L, Huk I, Mailnski T. VEGF-nitric oxide reciprocal regulation Nat Med. 1997 Nov;3(11):1177. PubMed PMID: 9359669 !
Huk I, Nanobashvili J, Neumayer C, Punz A, Mueller M, Afkhampour K, Mittlboeck M, Losert U, Polterauer P, Roth E, Patton S, Malinski T. L-arginine treatment alters the kinetics of nitric oxide and superoxide release and reduces ischemia/reperfusion injury in skeletal muscle. Circulation. 1997 Jul 15;96(2):667-75. PubMed PMID: 9244241 !
Cohen RA, Plane F, Najibi S, Huk I, Malinski T, Garland CJ. Nitric oxide is the mediator of both endothelium-dependent relaxation and hyperpolarization of the rabbit carotid artery Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):4193-8. PubMed PMID: 9108128; PubMed Central PMCID: PMC20600.