Univ.-Prof. Dr. med. Guido Gerken - Gastroenterologie, Essen - Publikationen

El, F. A.; Ertle, J.; El, D. A.; Shaker, M. K.; Dechene, A.; Abdella, H.; Mueller, S.; Barakat, E.; Lauenstein, T.; Bockisch, A.; Gerken, G.; Schlaak, J. F. In Intermediate Stage Hepatocellular Carcinoma: Radioembolization With Yttrium 90 or Chemoembolization? Liver Int. 2015, 35, 627-635.

Frank, M.; Hennenberg, E. M.; Eyking, A.; Runzi, M.; Gerken, G.; Scott, P.; Parkhill, J.; Walker, A. W.; Cario, E. TLR Signaling Modulates Side Effects of Anticancer Therapy in the Small Intestine. J. Immunol. 2015.

Hahnemann, M. L.; Nensa, F.; Kinner, S.; Gerken, G.; Lauenstein, T. C. Motility Mapping As Evaluation Tool for Bowel Motility: Initial Results on the Development of an Automated Color-Coding Algorithm in Cine MRI. J. Magn Reson. Imaging 2015, 41, 354-360.

Hahnemann, M. L.; Nensa, F.; Kinner, S.; Maderwald, S.; Umutlu, L.; Gerken, G.; Lauenstein, T. C. Improved Detection of Inflammatory Bowel Disease by Additional Automated Motility Analysis in Magnetic Resonance Imaging. Invest Radiol. 2015, 50, 67-72.

Kefalakes, H.; Jochum, C.; Hilgard, G.; Kahraman, A.; Bohrer, A. M.; Hindy, N. E.; Heinemann, F. M.; Verheyen, J.; Gerken, G.; Roggendorf, M.; Timm, J. Decades After Recovery From Hepatitis B and HBsAg Clearance the CD8 T Cell Response Against HBV Core Is Nearly Undetectable. J. Hepatol. 2015.

Piras-Straub, K.; Khairzada, K.; Trippler, M.; Baba, H. A.; Kaiser, G. M.; Paul, A.; Canbay, A.; Weber, F.; Gerken, G.; Herzer, K. TRAIL Expression Levels in Human Hepatocellular Carcinoma Have Implications for Tumor Growth, Recurrence and Survival. Int. J. Cancer 2015, 136, E154-E160.

Baraniskin, A.; Nopel-Dunnebacke, S.; Schumacher, B.; Gerges, C.; Bracht, T.; Sitek, B.; Meyer, H. E.; Gerken, G.; Dechene, A.; Schlaak, J. F.; Schroers, R.; Pox, C.; Schmiegel, W.; Hahn, S. A. Analysis of U2 Small Nuclear RNA Fragments in the Bile Differentiates Cholangiocarcinoma From Primary Sclerosing Cholangitis and Other Benign Biliary Disorders. Dig. Dis. Sci. 2014, 59, 1436-1441.

Beilfuss, A.; Sowa, J. P.; Sydor, S.; Beste, M.; Bechmann, L. P.; Schlattjan, M.; Syn, W. K.; Wedemeyer, I.; Mathe, Z.; Jochum, C.; Gerken, G.; Gieseler, R. K.; Canbay, A. Vitamin D Counteracts Fibrogenic TGF-Beta Signalling in Human Hepatic Stellate Cells Both Receptor-Dependently and Independently. Gut 2014.

Broering, R.; Real, C. I.; John, M. J.; Jahn-Hofmann, K.; Ickenstein, L. M.; Kleinehr, K.; Paul, A.; Gibbert, K.; Dittmer, U.; Gerken, G.; Schlaak, J. F. Chemical Modifications on SiRNAs Avoid Toll-Like-Receptor-Mediated Activation of the Hepatic Immune System in Vivo and in Vitro. Int. Immunol. 2014, 26, 35-46.

Dechene, A.; Kodde, C.; Kathemann, S.; Treckmann, J.; Lainka, E.; Paul, A.; Gerken, G.; Feldstein, A. E.; Hoyer, P. F.; Canbay, A. Endoscopic Treatment of Pediatric Post-Transplant Biliary Complications Is Safe and Effective. Dig. Endosc. 2014.

Dechene, A.; Sowa, J. P.; Schlattjan, M.; Wree, A.; Blomeyer, S.; Best, J.; Maldonado, E. J.; Bechmann, L. P.; Gerken, G.; Baba, H. A.; Syn, W. K.; Canbay, A. Mini-Laparoscopy Guided Liver Biopsy Increases Diagnostic Accuracy in Acute Liver Failure. Digestion 2014, 90, 240-247.

Dechene, A.; Jochum, C.; Fingas, C.; Paul, A.; Heider, D.; Syn, W. K.; Gerken, G.; Canbay, A.; Zopf, T. Endoscopic Management Is the Treatment of Choice for Bile Leaks After Liver Resection. Gastrointest. Endosc. 2014, 80, 626-633.

Herzer, K.; Gerken, G.; Hofmann, T. G. Hepatitis C-Associated Liver Carcinogenesis: Role of PML Nuclear Bodies. World J. Gastroenterol. 2014, 20, 12367-12371.

Hoyo-Becerra, C.; Liu, Z.; Yao, J.; Kaltwasser, B.; Gerken, G.; Hermann, D. M.; Schlaak, J. F. Rapid Regulation of Depression-Associated Genes in a New Mouse Model Mimicking Interferon-Alpha-Related Depression in Hepatitis C Virus Infection. Mol. Neurobiol. 2014.

Koch, A.; Zimmermann, H. W.; Gassler, N.; Jochum, C.; Weiskirchen, R.; Bruensing, J.; Buendgens, L.; Duckers, H.; Bruns, T.; Gerken, G.; Neumann, U. P.; Adams, D. H.; Trautwein, C.; Canbay, A.; Tacke, F. Clinical Relevance and Cellular Source of Elevated Soluble Urokinase Plasminogen Activator Receptor (SuPAR) in Acute Liver Failure. Liver Int. 2014, 34, 1330-1339.

Manka, P.; Olliges, V.; Bechmann, L. P.; Schlattjan, M.; Jochum, C.; Treckmann, J. W.; Saner, F. H.; Gerken, G.; Syn, W. K.; Canbay, A. Low Levels of Blood Lipids Are Associated With Etiology and Lethal Outcome in Acute Liver Failure. PLoS. One. 2014, 9, e102351.

Manns, M.; Pol, S.; Jacobson, I. M.; Marcellin, P.; Gordon, S. C.; Peng, C. Y.; Chang, T. T.; Everson, G. T.; Heo, J.; Gerken, G.; Yoffe, B.; Towner, W. J.; Bourliere, M.; Metivier, S.; Chu, C. J.; Sievert, W.; Bronowicki, J. P.; Thabut, D.; Lee, Y. J.; Kao, J. H.; McPhee, F.; Kopit, J.; Mendez, P.; Linaberry, M.; Hughes, E.; Noviello, S. All-Oral Daclatasvir Plus Asunaprevir for Hepatitis C Virus Genotype 1b: a Multinational, Phase 3, Multicohort Study. Lancet 2014, 384, 1597-1605.

Papadopoulos-Kohn, A.; Achterfeld, A.; Paul, A.; Canbay, A.; Timm, J.; Jochum, C.; Gerken, G.; Herzer, K. Daily Low-Dose Tacrolimus Is a Safe and Effective Immunosuppressive Regimen During Telaprevir-Based Triple Therapy for Hepatitis C Virus Recurrence After Liver Transplant. Transplantation 2014.

Paul, A.; Sotiropoulos, G.; Gerken, G.; Saner, F. H. How to Decide About Liver Transplantation in Patients With Hepatocellular Carcinoma: Size and Number of Lesions or Response to TACE? J. Hepatol. 2014, 60, 463-464.

Schelhorn, J.; Best, J.; Reinboldt, M. P.; Dechene, A.; Gerken, G.; Ruhlmann, M.; Lauenstein, T. C.; Antoch, G.; Kinner, S. Does Diffusion-Weighted Imaging Improve Therapy Response Evaluation in Patients With Hepatocellular Carcinoma After Radioembolization? Comparison of MRI Using Gd-EOB-DTPA With and Without DWI. J. Magn Reson. Imaging 2014.

Sowa, J. P.; Gerken, G.; Canbay, A. From Bedside to Bench and Back Again-Molecular Mechanisms in Acute Liver Failure. Front Physiol 2014, 5, 18.

Sowa, J. P.; Atmaca, O.; Kahraman, A.; Schlattjan, M.; Lindner, M.; Sydor, S.; Scherbaum, N.; Lackner, K.; Gerken, G.; Heider, D.; Arteel, G. E.; Erim, Y.; Canbay, A. Non-Invasive Separation of Alcoholic and Non-Alcoholic Liver Disease With Predictive Modeling. PLoS. One. 2014, 9, e101444.

Varnavas, V. C.; Reinsch, N.; Perrey, M.; Nensa, F.; Schlosser, T.; Baba, H. A.; Gerken, G.; Erbel, R.; Janosi, R. A.; Katsounas, A. Recurrent Lymphocytic Myocarditis in a Young Male With Ulcerative Colitis. Eur. J. Med. Res. 2014, 19, 11.

Wree, A.; Schlattjan, M.; Bechmann, L. P.; Claudel, T.; Sowa, J. P.; Stojakovic, T.; Scharnagl, H.; Kofeler, H.; Baba, H. A.; Gerken, G.; Feldstein, A. E.; Trauner, M.; Canbay, A. Adipocyte Cell Size, Free Fatty Acids and Apolipoproteins Are Associated With Non-Alcoholic Liver Injury Progression in Severely Obese Patients. Metabolism 2014, 63, 1542-1552.

Bechmann, L. P.; Kocabayoglu, P.; Sowa, J. P.; Sydor, S.; Best, J.; Schlattjan, M.; Beilfuss, A.; Schmitt, J.; Hannivoort, R. A.; Kilicarslan, A.; Rust, C.; Berr, F.; Tschopp, O.; Gerken, G.; Friedman, S. L.; Geier, A.; Canbay, A. Free Fatty Acids Repress Small Heterodimer Partner (SHP) Activation and Adiponectin Counteracts Bile Acid-Induced Liver Injury in Superobese Patients With Nonalcoholic Steatohepatitis. Hepatology 2013, 57, 1394-1406.

Ertle, J. M.; Heider, D.; Wichert, M.; Keller, B.; Kueper, R.; Hilgard, P.; Gerken, G.; Schlaak, J. F. A Combination of Alpha-Fetoprotein and Des-Gamma-Carboxy Prothrombin Is Superior in Detection of Hepatocellular Carcinoma. Digestion 2013, 87, 121-131.

Ey, B.; Eyking, A.; Klepak, M.; Salzman, N. H.; Gothert, J. R.; Runzi, M.; Schmid, K. W.; Gerken, G.; Podolsky, D. K.; Cario, E. Loss of TLR2 Worsens Spontaneous Colitis in MDR1A Deficiency Through Commensally Induced Pyroptosis. J. Immunol. 2013, 190, 5676-5688.

Fingas, C. D.; Altinbas, A.; Schlattjan, M.; Beilfuss, A.; Sowa, J. P.; Sydor, S.; Bechmann, L. P.; Ertle, J.; Akkiz, H.; Herzer, K.; Paul, A.; Gerken, G.; Baba, H. A.; Canbay, A. Expression of Apoptosis- and Vitamin D Pathway-Related Genes in Hepatocellular Carcinoma. Digestion 2013, 87, 176-181.

Gu, Y.; Sowa, J. P.; Paul, A.; Gerken, G.; Schlaak, J. F. Vascular Endothelial Growth Factor Improves Liver Regeneration and Survival After 90% Hepatectomy in a Rat Model of Diet-Induced Steatosis. Digestion 2013, 88, 235-242.

Hinz, M.; Wree, A.; Jochum, C.; Bechmann, L. P.; Saner, F.; Gerbes, A. L.; Gerken, G.; Canbay, A. High Age and Low Sodium Urine Concentration Are Associated With Poor Survival in Patients With Hepatorenal Syndrome. Ann. Hepatol. 2013, 12, 92-99.

Hoyo-Becerra, C.; Huebener, A.; Trippler, M.; Lutterbeck, M.; Liu, Z. J.; Truebner, K.; Bajanowski, T.; Gerken, G.; Hermann, D. M.; Schlaak, J. F. Concomitant Interferon Alpha Stimulation and TLR3 Activation Induces Neuronal Expression of Depression-Related Genes That Are Elevated in the Brain of Suicidal Persons. PLoS. One. 2013, 8, e83149.

Juntermanns, B.; Sotiropoulos, G. C.; Radunz, S.; Reis, H.; Heuer, M.; Baba, H. A.; Canbay, A.; Schuler, M.; Gerken, G.; Paul, A.; Kaiser, G. M. Comparison of the Sixth and the Seventh Editions of the UICC Classification for Perihilar Cholangiocarcinoma. Ann. Surg. Oncol. 2013, 20, 277-284.

Kahraman, A.; Sowa, J. P.; Schlattjan, M.; Sydor, S.; Pronadl, M.; Wree, A.; Beilfuss, A.; Kilicarslan, A.; Altinbas, A.; Bechmann, L. P.; Syn, W. K.; Gerken, G.; Canbay, A. Fetuin-A MRNA Expression Is Elevated in NASH Compared With NAFL Patients. Clin. Sci. (Lond) 2013, 125, 391-400.

Kaiser, G. M.; Paul, A.; Sgourakis, G.; Molmenti, E. P.; Dechene, A.; Trarbach, T.; Stuschke, M.; Baba, H. A.; Gerken, G.; Sotiropoulos, G. C. Novel Prognostic Scoring System After Surgery for Klatskin Tumor. Am. Surg. 2013, 79, 90-95.

Krawczyk, A.; Roggendorf, H.; Ludwig, C.; Herzer, K.; Gerken, G.; Horn, P. A.; Roggendorf, M.; Lindemann, M. Therapeutic Vaccination of a Liver Transplant Recipient Suffering From Fulminant Hepatitis B During Pregnancy. Liver Transpl. 2013, 19, 1411-1412.

Manka, P.; Bechmann, L. P.; Tacke, F.; Sowa, J. P.; Schlattjan, M.; Kalsch, J.; Jochum, C.; Paul, A.; Saner, F. H.; Trautwein, C.; Gerken, G.; Canbay, A. Serum Sodium Based Modification of the MELD Does Not Improve Prediction of Outcome in Acute Liver Failure. BMC. Gastroenterol. 2013, 13, 58.

Real, C. I.; Megger, D. A.; Sitek, B.; Jahn-Hofmann, K.; Ickenstein, L. M.; John, M. J.; Walker, A.; Timm, J.; Kuhlmann, K.; Eisenacher, M.; Meyer, H. E.; Gerken, G.; Broering, R.; Schlaak, J. F. Identification of Proteins That Mediate the Pro-Viral Functions of the Interferon Stimulated Gene 15 in Hepatitis C Virus Replication. Antiviral Res. 2013, 100, 654-661.

Reimer, J.; Schmidt, C. S.; Schulte, B.; Gansefort, D.; Golz, J.; Gerken, G.; Scherbaum, N.; Verthein, U.; Backmund, M. Psychoeducation Improves Hepatitis C Virus Treatment During Opioid Substitution Therapy: a Controlled, Prospective Multicenter Trial. Clin. Infect. Dis. 2013, 57 Suppl 2, S97-104.

Santoro, A.; Rimassa, L.; Borbath, I.; Daniele, B.; Salvagni, S.; Van Laethem, J. L.; Van, V. H.; Trojan, J.; Kolligs, F. T.; Weiss, A.; Miles, S.; Gasbarrini, A.; Lencioni, M.; Cicalese, L.; Sherman, M.; Gridelli, C.; Buggisch, P.; Gerken, G.; Schmid, R. M.; Boni, C.; Personeni, N.; Hassoun, Z.; Abbadessa, G.; Schwartz, B.; Von, R. R.; Lamar, M. E.; Chen, Y.; Porta, C. Tivantinib for Second-Line Treatment of Advanced Hepatocellular Carcinoma: a Randomised, Placebo-Controlled Phase 2 Study. Lancet Oncol. 2013, 14, 55-63.

Sowa, J. P.; Heider, D.; Bechmann, L. P.; Gerken, G.; Hoffmann, D.; Canbay, A. Novel Algorithm for Non-Invasive Assessment of Fibrosis in NAFLD. PLoS. One. 2013, 8, e62439.

Sydor, S.; Gu, Y.; Schlattjan, M.; Bechmann, L. P.; Rauen, U.; Best, J.; Paul, A.; Baba, H. A.; Sowa, J. P.; Gerken, G.; Canbay, A. Steatosis Does Not Impair Liver Regeneration After Partial Hepatectomy. Lab Invest 2013, 93, 20-30.

Weng, Z.; Ertle, J.; Zheng, S.; Lauenstein, T.; Mueller, S.; Bockisch, A.; Gerken, G.; Yang, D.; Schlaak, J. F. A New Model to Estimate Prognosis in Patients With Hepatocellular Carcinoma After Yttrium-90 Radioembolization. PLoS. One. 2013, 8, e82225.

Weng, Z.; Ertle, J.; Zheng, S.; Lauenstein, T.; Mueller, S.; Bockisch, A.; Gerken, G.; Yang, D.; Schlaak, J. F. Choi Criteria Are Superior in Evaluating Tumor Response in Patients Treated With Transarterial Radioembolization for Hepatocellular Carcinoma. Oncol. Lett. 2013, 6, 1707-1712.

Professor Gerken hat in den letzten zehn Jahren mehr als 600 wissenschaftliche Publikationen in mehr als 150 wissenschaftlichen Zeitschriften veröffentlicht.