Prof. Dr. med. Lars E. French - Haut- und Geschlechtskrankheiten, Zürich - Publikationen

Chapman PB, Hauschild A, Robert C, Haanen JB, Ascierto P, Larkin J, Dummer R, Garbe C, Testori A, Maio M, Hogg D, Lorigan P, Lebbe C, Jouary T, Schadendorf D, Ribas A, O'Day SJ, Sosman JA, Kirkwood JM, Eggermont AM, Dreno B, Nolop K, Li J, Nelson B, Hou J, Lee RJ, Flaherty KT, McArthur AG; BRIM-3 Study Group. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 364; 2507, 2011

Martorell hypertensive ischemic leg ulcer: a model of ischemic subcutaneous arteriolosclerosis.
Hafner J, Nobbe S, Partsch H, Läuchli S, Mayer D, Amann-Vesti B, Speich R, Schmid C, Burg G, French LE. Arch Dermatol. 146:961-8, 2010

Severe cutaneous adverse reactions: acute generalized exanthematous pustulosis, toxic epidermal necrolysis and Stevens-Johnson syndrome. Harr T, French LE. Med Clin North Am. 94:727-42, 2010

The mTOR inhibitor rapamycin significantly improves facial angiofibroma lesions in a patient with tuberous.  sclerosis. Hofbauer GF, Marcollo-Pini A, Corsenca A, Kistler AD, French LE, Wüthrich RP, Serra AL. Br J Dermatol. 159:473-5, 2008

Resistance to FasL and tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in Sezary syndrome T-cells associated with impaired death receptor and FLICE-inhibitory protein expression. Contassot E, Kerl K, Roques S, Shane R, Gaide O, Dupuis M, Rook AH, French LE. Blood. 111:4780-7, 2008

Clemastine causes immune suppression through inhibition of extracellular signal-regulated kinase-dependent proinflammatory cytokines. Johansen P, Weiss A, Bünter A, Waeckerle-Men Y, Fettelschoss A, Odermatt B, Kündig TM.
J Allergy Clin Immunol. 2011, July 30 [E pub ahead of print]

Epicutaneous allergen administration as a novel method of allergen-specific immunotherapy.
Senti G, Graf N, Haug S, Rüedi N, von Moos S, Sonderegger T, Johansen P, Kündig TM.
J Allergy Clin Immunol. 124; 997-1002. 2009

Intralymphatic allergen administration renders specific immunotherapy faster and safer: a randomized controlled trial.
Senti G, Prinz Vavricka BM, Erdmann I, Diaz MI, Markus R, McCormack SJ, Simard JJ, Wüthrich B, Crameri R, Graf N, Johansen P, Kündig TM.
Proc Natl Acad Sci U S A. 105: 17908-12, 2008

Antigen kinetics determines immune reactivity.
Johansen P, Storni T, Rettig L, Qiu Z, Der-Sarkissian A, Smith KA, Manolova V, Lang KS, Senti G, Müllhaupt B, Gerlach T, Speck RF, Bot A, Kündig TM.
Proc Natl Acad Sci U S A .105: 5189-94, 2088

Krieg C, Létourneau S, Pantaleo G, Boyman O. Improved IL-2 immunotherapy by selective stimulation of IL-2 receptors on lymphocytes and endothelial cells. Proc Natl Acad Sci U S A. 107:11906-11, 2010